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The annual bushy plant Centratherum punctutam Cass. is one of 33 species in the genus Centratherum and has a diameter of 45-60 cm. It has purple flower heads and a strong stem with reviving aromatic leaves. Its leaves have recently provided an important oil that contains around 59 different compounds. Centratherin, a sesquiterpene lactone found in Centratherum punctatum, was identified, but its therapeutic properties remained unknown. A closely related genus, Centratherum anthelminticum, possesses anti-filarial and anti-hyperglycemic properties.
The test drug both in 200 mg and 400 mg shows potent anti-diabetic activity in comparison to standard marketed anti-diabetic drug Glibenclamide.
Leaves of C. punctatum shows potent antidiabetic activity and have a scope for the treatment, isolation for particular patients